解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The present study attempted to demonstrate that the indicator arm influences end point distribution in contralateral multi-joint proprioceptive tasks and also that intrinsic physical characteristics of multi-joint arms (arm stiffness) may predict the error pattern. For this purpose, we carried out two types of contral...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3196-3
更新日期:2012-10-01 00:00:00
abstract::We explored digit coordination during the acceleration phase of a quick lifting movement of a hand-held horizontal object. We tested three hypotheses related to: (1) the scaling of mechanical variables produced by the hand with changes in the external load, torque, and moment of inertia; (2) changes in the safety marg...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3215-4
更新日期:2012-10-01 00:00:00
abstract::By studying human movement in the laboratory, a number of regularities and invariants such as planarity and the principle of isochrony have been discovered. The theoretical idea has gained traction that movement may be generated from a limited set of movement primitives that would encode these invariants. In this stud...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3205-6
更新日期:2012-10-01 00:00:00
abstract::Our recent work has revealed that visuospatial working memory (VSWM) relates to the rate of explicit motor sequence learning (Bo and Seidler in J Neurophysiol 101:3116-3125, 2009) and implicit sequence performance (Bo et al. in Exp Brain Res 214:73-81, 2011a) in young adults (YA). Although aging has a detrimental impa...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3189-2
更新日期:2012-09-01 00:00:00
abstract::Gait is recognized as a key item related to mental function. Anomalous gait in psychotic individuals has been described for the lower extremities, whereas irregularities for upper body dynamics are not described, explained or verified with unbiased methods. Reduced walking velocity and increased somatic tension define...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-012-3184-7
更新日期:2012-09-01 00:00:00
abstract::The current study examined whether the amount and location of available movement information influenced the stability of visuomotor coordination. Participants coordinated a handheld pendulum with an oscillating visual stimulus in an inphase and antiphase manner. The effects of occluding different amounts of phase at d...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1982-3
更新日期:2012-09-01 00:00:00
abstract::Primary somatosensory cortex (S1) is known to rapidly adapt to task demands and to intermodal information (e.g. from vision). Here, we show that also intramodal information (i.e. posture) can affect tactile attentional selection processes and the intermodal effects of vision on those processes at S1 stages of processi...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-012-3171-z
更新日期:2012-09-01 00:00:00
abstract::Transcranial direct current stimulation (tDCS) induces cortical excitability changes in animals and humans that can last beyond the duration of stimulation. Preliminary evidence suggests that tDCS may have an analgesic effect; however, the timing of these effects, especially when associated with consecutive sessions o...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3149-x
更新日期:2012-08-01 00:00:00
abstract::The arm movement control system often relies on visual feedback to drive motor adaptation and to help specify desired trajectories. Here we studied whether kinematic errors that were indicated with auditory feedback could be used to control reaching in a way comparable with when vision was available. We randomized twe...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-012-3144-2
更新日期:2012-08-01 00:00:00
abstract::Preshaping the digits and orienting the hand when reaching to grasp a distal target is proposed to be optimal when guided by vision. A reach-to-grasp movement to an object in one's own mouth is a natural and commonly used movement, but there has been no previous description of how it is performed. The movement require...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3164-y
更新日期:2012-08-01 00:00:00
abstract::Sensorimotor synchronization is hypothesized to arise through two different processes, associated with continuous or discontinuous rhythmic movements. This study investigated synchronization of continuous and discontinuous movements to different pacing signals (auditory or visual), pacing interval (500, 650, 800, 950 ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3142-4
更新日期:2012-08-01 00:00:00
abstract::It is a common experience, immediately after the removal of a cast or a splint, to feel motor awkwardness, which is usually attributed to muscular and joint immobilization. However, the same feeling may also be perceived after a brief period of immobilization. We provide evidence that this last effect stems from chang...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3115-7
更新日期:2012-07-01 00:00:00
abstract::Precise left-hand movements take longer than right-hand movements (for right-handers). To quantify how left-hand movements are affected by task difficulty and phase of movement control, we manipulated the difficulty of repetitive speeded aiming movements while participants used the left or right hand. We observed left...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3110-z
更新日期:2012-07-01 00:00:00
abstract::Eye and head rotations are normally correlated with changes in walking direction; however, it is unknown whether they play a causal role in the control of steering. The objective of the present study was to answer two questions about the role of head rotations in steering control when walking to a goal. First, are hea...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3077-9
更新日期:2012-06-01 00:00:00
abstract::In this study, we examined the relationship between a measure of cerebral lateralization--differences in tympanic temperature (T(Ty))--and questionnaire measures of inattentiveness and hyperactivity in both people and dogs. Theories of cerebral lateralization indicate that cerebral asymmetry may improve attentive beha...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3093-9
更新日期:2012-06-01 00:00:00
abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3090-z
更新日期:2012-06-01 00:00:00
abstract::Perception of whether a given behavior is possible typically reflects a person's action capabilities even before the behavior is performed and even when the person has undergone recent changes to their action capabilities. Importantly, perception of affordances for a given behavior also reflects impending changes to a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3104-x
更新日期:2012-06-01 00:00:00
abstract::This study investigated the modulation of somatosensory evoked potentials (SEPs) during precisely controlled force generation and force relaxation in a visuomotor tracking task. Subjects were instructed to track a target line with a line that represented their own force generated by grip movement with the right hand a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3082-z
更新日期:2012-06-01 00:00:00
abstract::Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3026-7
更新日期:2012-05-01 00:00:00
abstract::Pain catastrophizing has been associated with phantom limb pain, but so far the cortical processes and the brain regions involved in this relationship have not been investigated. It was therefore tested whether catastrophizing was related to (1) spontaneous pain, (2) somatosensory activity and (3) cortical responses i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3027-6
更新日期:2012-05-01 00:00:00
abstract::Our previous study showed that a fully flexed or extended hand became perceived as an extended or flexed 'phantom' hand as ischemic anesthesia progressed (Inui et al. in J Physiol 589:5775-5784, 2011). Here, we examined what happened if the hand was held in the midposition before and during the anesthesia. Twenty heal...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3040-9
更新日期:2012-05-01 00:00:00
abstract::Linear and angular control of trunk and leg motion during curvilinear navigation was investigated in subjects with cerebellar ataxia and age-matched control subjects. Subjects walked with eyes open around a 1.2-m circle. The relationship of linear to angular motion was quantified by determining the ratios of trunk lin...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3074-z
更新日期:2012-05-01 00:00:00
abstract::Mental imagery is considered to be important for normal conscious experience. It is most frequently investigated in the visual, auditory and motor domain (imagination of movement), while the studies on tactile imagery (imagination of touch) are scarce. The current study investigated the effect of tactile and auditory ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3020-0
更新日期:2012-05-01 00:00:00
abstract::The present study aimed at determining whether the observation of two functionally compatible artefacts, that is which potentially concur in achieving a specific function, automatically activates a motor programme of interaction between the two objects. To this purpose, an interference paradigm was used during which a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3047-2
更新日期:2012-05-01 00:00:00
abstract::Modern tools in technological environments are often characterized by a spatial separation of hand actions (operating a remote control) and their intended action effects (displayed movements of an unmanned vehicle, a robot, or an avatar on a screen). Often non-corresponding proximal and distal movement effects put hig...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3018-7
更新日期:2012-04-01 00:00:00
abstract::The presence of after-effects in adaptation tasks implies that an existing internal model has been updated. Previously, we showed that although observers adapted to a visuomotor perturbation, they did not show after-effects. In this experiment, we tested 2 further observer groups and an actor group. Observers were now...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2996-1
更新日期:2012-04-01 00:00:00
abstract::The amyloid precursor protein (APP) is one of the key proteins in Alzheimer's disease (AD), as it is the precursor of amyloid β (Aβ) peptides accumulating in amyloid plaques. The processing of APP and the pathogenic features of especially Aβ oligomers have been analyzed in detail. Remarkably, there is accumulating evi...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2878-6
更新日期:2012-04-01 00:00:00
abstract::The amyloid precursor protein (APP) has a pivotal role in pathogenesis of Alzheimer's disease (AD) via its beta- and gamma-secretase-derived cleavage products--the A-beta peptides. An alternative processing pathway provided by the alpha-secretase prevents formation of those toxic peptides and gives rise to the neurotr...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2885-7
更新日期:2012-04-01 00:00:00
abstract::APP, APLP1, and APLP2 form a family of mammalian membrane proteins with unknown function. APP, however, plays a key role in the molecular pathology of Alzheimer's disease (AD), indicating that it is somehow involved in synaptic transmission, synaptic plasticity, memory formation, and maintenance of neurons. At present...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2894-6
更新日期:2012-04-01 00:00:00
abstract::We have shown before that subjects exposed to a changed gravitoinertial environment produce exaggerated manual forces. From the observed pattern of findings, we argued that initial forces were exaggerated because of abnormal vestibular activity and peak forces because of degraded proprioceptive feedback. If so, only p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-2999-6
更新日期:2012-04-01 00:00:00
abstract::We investigated whether the control of movement of the left hand is more likely to involve the use of allocentric information than movements performed with the right hand. Previous studies (Gonzalez et al. in J Neurophys 95:3496-3501, 2006; De Grave et al. in Exp Br Res 193:421-427, 2009) have reported contradictory f...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3007-x
更新日期:2012-04-01 00:00:00
abstract::Optimal levels of noise stimulation have been shown to enhance the detection and transmission of neural signals thereby improving the performance of sensory and motor systems. The first series of experiments in the present study aimed to investigate whether subsensory electrical noise stimulation applied over the tric...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2983-6
更新日期:2012-03-01 00:00:00
abstract::The aim of this study was to examine how adults processed common fractions with common numerators under two distinct conditions. Whereas participants were presented with only common fractions in a "simple" condition, a "complex" condition involved the random presentation of common fractions as well as decimal fraction...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2969-4
更新日期:2012-03-01 00:00:00
abstract::Three experiments examined interactions between posture control in upright stance and a concurrent location memory task. Healthy young participants stood upright and memorized the locations of dots presented on a computer screen. In the retrieval phase, they indicated whether arrows presented on the screen would pass ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2970-y
更新日期:2012-03-01 00:00:00
abstract::Previous work has shown that motoneurone excitability is enhanced by a hyperpolarization of the membrane potential at which an action potential is initiated (V(th)) at the onset, and throughout brainstem-evoked fictive locomotion in the adult decerebrate cat and neonatal rat. Modeling work has suggested the modulation...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2994-3
更新日期:2012-03-01 00:00:00
abstract::Prior reports have described a transient and focal decline in transcranial magnetic stimulation (TMS)-induced motor evoked potential (MEP) amplitude following fatiguing motor tasks. However, the neurophysiological causes of this change in MEP amplitude are unknown. The aim of this study was to determine whether post-t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2962-y
更新日期:2012-02-01 00:00:00
abstract::The current study examined the movement kinematics of older adults when aiming to vertically oriented targets. Late middle-age and early old-age participants completed 20 trials to a small target located downward or upward by 0.16 m from a home position at shoulder height. Aiming direction had a significant effect, re...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2947-x
更新日期:2012-02-01 00:00:00
abstract::The current study examined the EEG of young, old and old declined adults performing a visual paired associate task. In order to examine the effects of encoding context and stimulus repetition, target pairs were presented on either detailed or white backgrounds and were repeatedly presented during both early and late p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2966-7
更新日期:2012-02-01 00:00:00
abstract::This study investigated the importance of binocular vision to foot placement accuracy when stepping onto a floor-based target during gait initiation. Starting from stationary, participants placed alternate feet onto targets sequentially positioned along a straight travel path with the added constraint that the initial...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2910-x
更新日期:2012-01-01 00:00:00
abstract::During cerebral neocortical development, excitatory neurons are generated from radial glial cells in the ventricular zone (VZ) or from secondary progenitor cells in the subventricular zone (SVZ); these neurons then migrate toward the pial surface. We have observed that post-mitotic neurons generated directly in the VZ...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2933-3
更新日期:2012-01-01 00:00:00